John H. Hardeman, MD, DDS, discusses antihypertensive medications and their mechanisms of action, and management of the hypertensive patient in the dental setting. This article is peer reviewed and available for 2 hours of CE credit. Learning Objectives: After reading this article, the individual will learn: (1) classification and mechanism of action of antihypertensive medications, and (2) management of the hypertensive patient in the dental setting.