Anne Guignon, RDH, MPH, and Brian Nov?, DDS, discuss dry mouth syndrome and dental professionals? role in diagnosing and managing this condition. The emerging role of arginine-based technologies in the management of dry mouth syndrome is also discussed. This article is peer-reviewed and available for 2 hours of CE credit. Learning Objectives: After participating in this CE activity, the individual will learn: Causes and health complications of dry mouth syndrome and the dental professional?s role in diagnosing and managing this condition. The emerging role of arginine-based technologies in the management of dry mouth syndrome.